Cerulean Blue

You have to look at comic panelling like you look at directing a film. When you want somehting to happen, you'll get a good feel of what kind of shot you want, and what comes after. It usually helps to have a main idea of how you want a page to start and how you want it to end- those you be your first and last panels for that page. Then it's just filling the gap from point A to point B. Use a series of small closeup shots when something is being studied, use small expressional shots when you want to get characters' immediate facial reactions right before they make their next move, which should be a bigger panel, and always use a different zoom or camera angle each panel when focusing on the same thing for a while, and that'll keep things from looking like old Beavis and Butthead scenes where they're just snickering on their couch until sunrise.